4X69
Crystal structure of OP0595 complexed with CTX-M-44
Summary for 4X69
Entry DOI | 10.2210/pdb4x69/pdb |
Related | 4X68 |
Descriptor | Beta-lactamase Toho-1, (2S,5R)-N-(2-aminoethoxy)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, 1,2-ETHANEDIOL, ... (4 entities in total) |
Functional Keywords | hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Escherichia coli |
Total number of polymer chains | 2 |
Total formula weight | 57272.68 |
Authors | Yamada, M.,Watanabe, T. (deposition date: 2014-12-07, release date: 2015-07-01, Last modification date: 2023-11-08) |
Primary citation | Morinaka, A.,Tsutsumi, Y.,Yamada, M.,Suzuki, K.,Watanabe, T.,Abe, T.,Furuuchi, T.,Inamura, S.,Sakamaki, Y.,Mitsuhashi, N.,Ida, T.,Livermore, D.M. OP0595, a new diazabicyclooctane: mode of action as a serine beta-lactamase inhibitor, antibiotic and beta-lactam 'enhancer' J.Antimicrob.Chemother., 70:2779-2786, 2015 Cited by PubMed: 26089439DOI: 10.1093/jac/dkv166 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.42 Å) |
Structure validation
Download full validation report