4X5S
The crystal structure of an alpha carbonic anhydrase from the extremophilic bacterium Sulfurihydrogenibium azorense.
Summary for 4X5S
Entry DOI | 10.2210/pdb4x5s/pdb |
Descriptor | Carbonic anhydrase (Carbonate dehydratase), ZINC ION, 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, ... (5 entities in total) |
Functional Keywords | alpha bacterial carbonic anhydrase, enzyme-inhibitor complex, lyase |
Biological source | Sulfurihydrogenibium azorense |
Total number of polymer chains | 2 |
Total formula weight | 54606.56 |
Authors | De Simone, G.,Alterio, V.,Di Fiore, A. (deposition date: 2014-12-05, release date: 2015-05-20, Last modification date: 2024-01-10) |
Primary citation | De Simone, G.,Monti, S.M.,Alterio, V.,Buonanno, M.,De Luca, V.,Rossi, M.,Carginale, V.,Supuran, C.T.,Capasso, C.,Di Fiore, A. Crystal structure of the most catalytically effective carbonic anhydrase enzyme known, SazCA from the thermophilic bacterium Sulfurihydrogenibium azorense. Bioorg.Med.Chem.Lett., 25:2002-2006, 2015 Cited by PubMed: 25817590DOI: 10.1016/j.bmcl.2015.02.068 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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