4X5S

The crystal structure of an alpha carbonic anhydrase from the extremophilic bacterium Sulfurihydrogenibium azorense.

4X5S の概要

• エントリーDOI: 10.2210/pdb4x5s/pdb
• 分子名称: Carbonic anhydrase (Carbonate dehydratase), ZINC ION, 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, ... (5 entities in total)
• 機能のキーワード: alpha bacterial carbonic anhydrase, enzyme-inhibitor complex, lyase
• 由来する生物種: Sulfurihydrogenibium azorense
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 54606.56

構造登録者

De Simone, G.,Alterio, V.,Di Fiore, A. (登録日: 2014-12-05, 公開日: 2015-05-20, 最終更新日: 2024-01-10)

• 主引用文献: De Simone, G.,Monti, S.M.,Alterio, V.,Buonanno, M.,De Luca, V.,Rossi, M.,Carginale, V.,Supuran, C.T.,Capasso, C.,Di Fiore, A.; Crystal structure of the most catalytically effective carbonic anhydrase enzyme known, SazCA from the thermophilic bacterium Sulfurihydrogenibium azorense.; Bioorg.Med.Chem.Lett., 25:2002-2006, 2015; PubMed: 25817590; DOI: 10.1016/j.bmcl.2015.02.068

実験手法

X-RAY DIFFRACTION (1.95 Å)