4X3C

TORPEDO CALIFORNICA ACETYLCHOLINESTERASE IN COMPLEX WITH A TACRINE-NICOTINAMIDE HYBRID INHIBITOR

Summary for 4X3C

• Entry DOI: 10.2210/pdb4x3c/pdb
• Descriptor: Acetylcholinesterase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: multitarget drug, enzyme-inhibitor complex, tacrine, nicotinamide, hydrolase
• Biological source: Torpedo californica (Pacific electric ray)
• Cellular location: Isoform H: Cell membrane; Lipid-anchor, GPI- anchor. Isoform T: Cell membrane; Peripheral membrane protein: P04058
• Total number of polymer chains: 1
• Total formula weight: 61495.35

Authors

Pesaresi, A.,Lamba, D. (deposition date: 2014-11-28, release date: 2015-12-23, Last modification date: 2024-01-10)

• Primary citation: Pesaresi, A.,Lamba, D.; TORPEDO CALIFORNICA ACETYLCHOLINESTERASE IN COMPLEX WITH A TACRINE-NICOTINAMIDE HYBRID INHIBITOR; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.6 Å)