4X2A

Crystal structure of mouse glyoxalase I complexed with baicalein

Summary for 4X2A

Related2ZA0 4KYK
DescriptorLactoylglutathione lyase, ZINC ION, 5,6,7-trihydroxy-2-phenyl-4H-chromen-4-one, ... (4 entities in total)
Functional Keywordslyase, lyase-lyase inhibitor complex, lyase/lyase inhibitor
Biological sourceMus musculus (Mouse)
Total number of polymer chains2
Total molecular weight42342.46
Authors
Zhang, H.,Zhai, J.,Zhang, L.,Li, C.,Zhao, Y.,Hu, X. (deposition date: 2014-11-26, release date: 2015-09-16, Last modification date: 2015-10-28)
Primary citation
Zhang, H.,Zhai, J.,Zhang, L.,Li, C.,Zhao, Y.,Chen, Y.,Li, Q.,Hu, X.P.
In Vitro Inhibition of Glyoxalase by Flavonoids: New Insights from Crystallographic Analysis
Curr Top Med Chem, 16:460-466, 2016
PubMed: 26268338 (PDB entries with the same primary citation)
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.217500.7%3.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 4x2a
no rotation
Molmil generated image of 4x2a
rotated about x axis by 90°
Molmil generated image of 4x2a
rotated about y axis by 90°