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4X1N

The crystal structure of mupain-1-16 in complex with murinised human uPA at pH7.4

Summary for 4X1N
Entry DOI10.2210/pdb4x1n/pdb
Related4N1P 4N1Q 4N1R 4N1S 4X0W
Descriptormupain-1-16, Urokinase-type plasminogen activator, piperidine-1-carboximidamide, ... (4 entities in total)
Functional Keywordsserine protease, peptidic inhibitor, upa, hydrolase inhibitor-hydrolase complex, hydrolase inhibitor/hydrolase
Biological sourceHomo sapiens (Human)
More
Cellular locationSecreted: P00749
Total number of polymer chains2
Total formula weight29102.17
Authors
Jiang, L.,Zhao, B.,Xu, P.,Andreasen, P.,Huang, M. (deposition date: 2014-11-25, release date: 2015-03-25, Last modification date: 2023-11-08)
Primary citationZhao, B.,Xu, P.,Jiang, L.,Paaske, B.,Kromann-Hansen, T.,Jensen, J.K.,Srensen, H.P.,Liu, Z.,Nielsen, J.T.,Christensen, A.,Hosseini, M.,Srensen, K.K.,Nielsen, N.C.,Jensen, K.J.,Huang, M.,Andreasen, P.A.
A cyclic peptidic serine protease inhibitor: increasing affinity by increasing peptide flexibility.
Plos One, 9:e115872-e115872, 2014
Cited by
PubMed: 25545505
DOI: 10.1371/journal.pone.0115872
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.8 Å)
Structure validation

217705

数据于2024-03-27公开中

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