4X10

JC Polyomavirus genotype 3 VP1 in complex with GM2 oligosaccharide

4X10 の概要

• エントリーDOI: 10.2210/pdb4x10/pdb
• 関連するPDBエントリー: 3NXG
• 分子名称: Major capsid protein, N-acetyl-alpha-neuraminic acid-(2-3)-[2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)]beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, N-acetyl-alpha-neuraminic acid-(2-3)-[2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)]beta-D-galactopyranose, ... (7 entities in total)
• 機能のキーワード: beta-sandwich, jelly-roll, viral capsid protein, glycan, viral protein
• 由来する生物種: JC polyomavirus type 3 (JCPyV)
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 154544.57

構造登録者

Stroh, L.J.,Stehle, T. (登録日: 2014-11-24, 公開日: 2015-04-22, 最終更新日: 2024-01-10)

• 主引用文献: Stroh, L.J.,Maginnis, M.S.,Blaum, B.S.,Nelson, C.D.,Neu, U.,Gee, G.V.,O'Hara, B.A.,Motamedi, N.,DiMaio, D.,Atwood, W.J.,Stehle, T.; The Greater Affinity of JC Polyomavirus Capsid for alpha 2,6-Linked Lactoseries Tetrasaccharide c than for Other Sialylated Glycans Is a Major Determinant of Infectivity.; J.Virol., 89:6364-6375, 2015; PubMed: 25855729; DOI: 10.1128/JVI.00489-15

実験手法

X-RAY DIFFRACTION (1.9 Å)