4WYP

The crystal structure of the A109G mutant of RNase A in complex with 5'AMP

Summary for 4WYP

Entry DOI	10.2210/pdb4wyp/pdb
Related	4WYN
Descriptor	Ribonuclease pancreatic, ADENOSINE MONOPHOSPHATE (3 entities in total)
Functional Keywords	conformational dynamics, hydrolase
Biological source	Bos taurus (Bovine)
Total number of polymer chains	2
Total formula weight	28345.43
Authors	French, R.L.,Gagne, D.,Doucet, N.,Simonovic, M. (deposition date: 2014-11-17, release date: 2015-11-18, Last modification date: 2023-09-27)
Primary citation	Gagne, D.,French, R.L.,Narayanan, C.,Simonovic, M.,Agarwal, P.K.,Doucet, N. Perturbation of the Conformational Dynamics of an Active-Site Loop Alters Enzyme Activity. Structure, 23:2256-2266, 2015 Cited by PubMed: 26655472 DOI: 10.1016/j.str.2015.10.011 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.502 Å)

Structure validation