4WQN

Crystal structure of N6-methyladenosine RNA reader YTHDF2

Summary for 4WQN

Entry DOI	10.2210/pdb4wqn/pdb
Descriptor	YTH domain-containing family protein 2, GLYCEROL, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywords	n6-methyladenosine rna reader, rna binding protein
Biological source	Homo sapiens (Human)
Cellular location	Cytoplasm, P-body : Q9Y5A9
Total number of polymer chains	2
Total formula weight	40191.45
Authors	Zhu, T.,Roundtree, I.A.,Wang, P.,Wang, X.,Wang, L.,Sun, C.,Tian, Y.,Li, J.,He, C.,Xu, Y. (deposition date: 2014-10-22, release date: 2014-11-19, Last modification date: 2023-11-08)
Primary citation	Zhu, T.,Roundtree, I.A.,Wang, P.,Wang, X.,Wang, L.,Sun, C.,Tian, Y.,Li, J.,He, C.,Xu, Y. Crystal structure of the YTH domain of YTHDF2 reveals mechanism for recognition of N6-methyladenosine. Cell Res., 24:1493-1496, 2014 Cited by PubMed: 25412661 DOI: 10.1038/cr.2014.152 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.121 Å)

Structure validation