4WKA
Crystal structure of human chitotriosidase-1 catalytic domain at 0.95 A resolution
Summary for 4WKA
Entry DOI | 10.2210/pdb4wka/pdb |
Related | 1GUV |
Descriptor | Chitotriosidase-1, L(+)-TARTARIC ACID (3 entities in total) |
Functional Keywords | chit1, gh18 chitinase, protonation states, hydrolysis, catalytic mechanism, hydrolase |
Biological source | Homo sapiens (Human) |
Cellular location | Secreted: Q13231 |
Total number of polymer chains | 1 |
Total formula weight | 42524.46 |
Authors | Fadel, F.,Zhao, Y.,Cachau, R.,Cousido-Siah, A.,Ruiz, F.X.,Harlos, K.,Howard, E.,Mitschler, A.,Podjarny, A. (deposition date: 2014-10-02, release date: 2015-07-08, Last modification date: 2024-01-10) |
Primary citation | Fadel, F.,Zhao, Y.,Cachau, R.,Cousido-Siah, A.,Ruiz, F.X.,Harlos, K.,Howard, E.,Mitschler, A.,Podjarny, A. New insights into the enzymatic mechanism of human chitotriosidase (CHIT1) catalytic domain by atomic resolution X-ray diffraction and hybrid QM/MM. Acta Crystallogr.,Sect.D, 71:1455-1470, 2015 Cited by PubMed: 26143917DOI: 10.1107/S139900471500783X PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (0.95 Å) |
Structure validation
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