4WC8

Heterogeneous dodecamer formed from macrocycles containing a sequence from beta-2-microglobulin(63-69).

Summary for 4WC8

• Entry DOI: 10.2210/pdb4wc8/pdb
• Descriptor: ORN-TYR-LEU-LEU-PHI-TYR-THR-GLU-ORN-LYS-VAL-ALA-MAA-ALA-VAL-LYS, ORN-TYR-LEU-LEU-PHI-TYR-THR-GLU-ORN-LYS-VAL-ALA-MLE-ALA-VAL-LYS, SULFATE ION, ... (5 entities in total)
• Functional Keywords: heterogeneous dodecamer, hexamer, dimers, immune system
• Biological source: synthetic construct; More
• Total number of polymer chains: 12
• Total formula weight: 25654.05

Authors

Spencer, R.K.,Nowick, J.S. (deposition date: 2014-09-04, release date: 2015-05-06, Last modification date: 2023-12-27)

• Primary citation: Spencer, R.K.,Kreutzer, A.G.,Salveson, P.J.,Li, H.,Nowick, J.S.; X-ray Crystallographic Structures of Oligomers of Peptides Derived from beta 2-Microglobulin.; J.Am.Chem.Soc., 137:6304-6311, 2015; PubMed: 25915729; DOI: 10.1021/jacs.5b01673

Experimental method

X-RAY DIFFRACTION (1.908 Å)