4WA5

The crystal structure of neuraminidase from a H3N8 influenza virus isolated from New England harbor seals in complex with zanamivir

Summary for 4WA5

Entry DOI	10.2210/pdb4wa5/pdb
Related	4WA1 4WA2 4WA3 4WA4
Descriptor	Neuraminidase, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, ZANAMIVIR, ... (5 entities in total)
Functional Keywords	neuraminidase, influenza virus, seal, viral protein-inhibitor complex, viral protein/inhibitor
Biological source	Influenza A virus (A/harbor seal/Massachusetts/1/2011(H3N8))
Cellular location	Virion membrane : I6NW33
Total number of polymer chains	1
Total formula weight	43676.07
Authors	Yang, H.,Villanueva, J.M.,Gubareva, L.V.,Stevens, J. (deposition date: 2014-08-28, release date: 2015-01-14, Last modification date: 2023-12-27)
Primary citation	Yang, H.,Nguyen, H.T.,Carney, P.J.,Guo, Z.,Chang, J.C.,Jones, J.,Davis, C.T.,Villanueva, J.M.,Gubareva, L.V.,Stevens, J. Structural and Functional Analysis of Surface Proteins from an A(H3N8) Influenza Virus Isolated from New England Harbor Seals. J.Virol., 89:2801-2812, 2015 Cited by PubMed: 25540377 DOI: 10.1128/JVI.02723-14 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.95 Å)

Structure validation