4UNO

Crystal structure of the ETS domain of human ETV5 in complex with DNA

Summary for 4UNO

• Entry DOI: 10.2210/pdb4uno/pdb
• Descriptor: ETS TRANSLOCATION VARIANT 5, 5'-D(*AP*CP*CP*GP*GP*AP*AP*GP*TP*GP)-3', 5'-D(*AP*CP*TP*TP*CP*CP*GP*GP*TP*CP)-3', ... (5 entities in total)
• Functional Keywords: dna binding protein
• Biological source: HOMO SAPIENS (HUMAN); More
• Cellular location: Nucleus: P41161
• Total number of polymer chains: 3
• Total formula weight: 17973.74

Authors

Newman, J.A.,Aitkenhead, H.,Cooper, C.D.O.,Pinkas, D.M.,Shrestha, L.,Burgess-Brown, N.,Kopec, J.,Fitzpatrick, F.,Tallant, C.,von Delft, F.,Arrowsmith, C.H.,Bountra, C.,Edwards, A.,Gileadi, O. (deposition date: 2014-05-29, release date: 2014-06-11, Last modification date: 2024-01-10)

• Primary citation: Cooper, C.D.O.,Newman, J.A.,Aitkenhead, H.,Allerston, C.K.,Gileadi, O.; Structures of the Ets Domains of Transcription Factors Etv1, Etv4, Etv5 and Fev: Determinants of DNA Binding and Redox Regulation by Disulfide Bond Formation.; J.Biol.Chem., 290:13692-, 2015; PubMed: 25866208; DOI: 10.1074/JBC.M115.646737

Experimental method

X-RAY DIFFRACTION (1.95 Å)