4UJ2

Protein Kinase A in complex with an Inhibitor

4UJ2 の概要

• エントリーDOI: 10.2210/pdb4uj2/pdb
• 関連するPDBエントリー: 4UJ1 4UJ9 4UJA 4UJB
• 分子名称: CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA, CAMP-DEPENDENT PROTEIN KINASE INHIBITOR ALPHA, 7-[(3S,4R)-4-(3-iodanylphenyl)carbonylpyrrolidin-3-yl]-3H-quinazolin-4-one, ... (5 entities in total)
• 機能のキーワード: transferase-inhibitor complex, protein kinase a, transferase/inhibitor
• 由来する生物種: HOMO SAPIENS (HUMAN); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 43598.41

構造登録者

Alam, K.A.,Engh, R.A. (登録日: 2015-04-07, 公開日: 2016-04-13, 最終更新日: 2024-01-10)

• 主引用文献: Lauber, B.S.,Hardegger, L.A.,Asraful, A.K.,Lund, B.A.,Dumele, O.,Harder, M.,Kuhn, B.,Engh, R.A.,Diederich, F.; Addressing the Glycine-Rich Loop of Protein Kinases by a Multi-Facetted Interaction Network: Inhibition of Pka and a Pkb Mimic.; Chemistry, 22:211-, 2016; PubMed: 26578105; DOI: 10.1002/CHEM.201503552

実験手法

X-RAY DIFFRACTION (2.019 Å)