4UIM

crystal structure of quinine-dependent Fab 314.3

Summary for 4UIM

Related4UIK 4UIL 4UIN
DescriptorFAB 314.3, SULFATE ION, ... (4 entities in total)
Functional Keywordsimmune system, quinine-dependent, mouse mab
Biological sourceMUS MUSCULUS (HOUSE MOUSE)
Total number of polymer chains8
Total molecular weight191584.27
Authors
Zhu, J.,Zhu, J.,Bougie, D.W.,Aster, R.H.,Springer, T.A. (deposition date: 2015-03-30, release date: 2015-09-02, Last modification date: 2015-11-11)
Primary citation
Zhu, J.,Zhu, J.,Bougie, D.W.,Aster, R.H.,Springer, T.A.
Structural Basis for Quinine-Dependent Antibody Binding to Platelet Integrin Alphaiib Beta3
Blood, 126:2138-, 2015
PubMed: 26282540 (PDB entries with the same primary citation)
DOI: 10.1182/BLOOD-2015-04-639351
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.7 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.267120.6%2.9%3.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 4uim
no rotation
Molmil generated image of 4uim
rotated about x axis by 90°
Molmil generated image of 4uim
rotated about y axis by 90°