4UFM

Mouse Galactocerebrosidase complexed with 1-deoxy-galacto-nojirimycin DGJ

Summary for 4UFM

Entry DOI	10.2210/pdb4ufm/pdb
Related	4UFH 4UFI 4UFJ 4UFK 4UFL
Descriptor	GALACTOCEREBROSIDASE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, (2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol, ... (6 entities in total)
Functional Keywords	hydrolase, complex, lysosome
Biological source	MUS MUSCULUS (HOUSE MOUSE)
Cellular location	Lysosome : P54818
Total number of polymer chains	1
Total formula weight	76294.41
Authors	Hill, C.H.,Viuff, A.H.,Spratley, S.J.,Salamone, S.,Christensen, S.H.,Read, R.J.,Moriarty, N.W.,Jensen, H.H.,Deane, J.E. (deposition date: 2015-03-17, release date: 2015-04-01, Last modification date: 2023-12-20)
Primary citation	Hill, C.H.,Viuff, A.H.,Spratley, S.J.,Salamone, S.,Christensen, S.H.,Read, R.J.,Moriarty, N.W.,Jensen, H.H.,Deane, J.E. Azasugar Inhibitors as Pharmacological Chaperones for Krabbe Disease. Chem.Sci., 6:3075-, 2015 Cited by PubMed: 26029356 DOI: 10.1039/C5SC00754B PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation