4UBW
Apo structure of the 3-ketoacyl-CoA thiolase FadA5 from M. tuberculosis
Summary for 4UBW
| Entry DOI | 10.2210/pdb4ubw/pdb |
| Descriptor | Acetyl-CoA acetyltransferase FadA5, GLYCEROL, DIMETHYL SULFOXIDE, ... (6 entities in total) |
| Functional Keywords | degradative thiolase, apo, mycobacterium tuberculosis, cholesterol metabolism, transferase |
| Biological source | Mycobacterium tuberculosis H37Rv |
| Total number of polymer chains | 2 |
| Total formula weight | 87335.91 |
| Authors | Schaefer, C.M.,Kisker, C. (deposition date: 2014-08-13, release date: 2014-12-17, Last modification date: 2023-12-20) |
| Primary citation | Schaefer, C.M.,Lu, R.,Nesbitt, N.M.,Schiebel, J.,Sampson, N.S.,Kisker, C. FadA5 a Thiolase from Mycobacterium tuberculosis: A Steroid-Binding Pocket Reveals the Potential for Drug Development against Tuberculosis. Structure, 23:21-33, 2015 Cited by PubMed: 25482540DOI: 10.1016/j.str.2014.10.010 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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