4UBW

Apo structure of the 3-ketoacyl-CoA thiolase FadA5 from M. tuberculosis

4UBW の概要

• エントリーDOI: 10.2210/pdb4ubw/pdb
• 分子名称: Acetyl-CoA acetyltransferase FadA5, GLYCEROL, DIMETHYL SULFOXIDE, ... (6 entities in total)
• 機能のキーワード: degradative thiolase, apo, mycobacterium tuberculosis, cholesterol metabolism, transferase
• 由来する生物種: Mycobacterium tuberculosis H37Rv
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 87335.91

構造登録者

Schaefer, C.M.,Kisker, C. (登録日: 2014-08-13, 公開日: 2014-12-17, 最終更新日: 2023-12-20)

• 主引用文献: Schaefer, C.M.,Lu, R.,Nesbitt, N.M.,Schiebel, J.,Sampson, N.S.,Kisker, C.; FadA5 a Thiolase from Mycobacterium tuberculosis: A Steroid-Binding Pocket Reveals the Potential for Drug Development against Tuberculosis.; Structure, 23:21-33, 2015; PubMed: 25482540; DOI: 10.1016/j.str.2014.10.010

実験手法

X-RAY DIFFRACTION (2.7 Å)