4UAK
MRCK beta in complex with ADP
Summary for 4UAK
Entry DOI | 10.2210/pdb4uak/pdb |
Descriptor | Serine/threonine-protein kinase MRCK beta, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (6 entities in total) |
Functional Keywords | myotonic dystrophy kinase-related cdc42-binding kinase, metastasis, cell invasion, transferase |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasm : Q9Y5S2 |
Total number of polymer chains | 1 |
Total formula weight | 48632.15 |
Authors | Schuettelkopf, A.W. (deposition date: 2014-08-10, release date: 2014-10-22, Last modification date: 2023-12-20) |
Primary citation | Unbekandt, M.,Croft, D.R.,Crighton, D.,Mezna, M.,McArthur, D.,McConnell, P.,Schuttelkopf, A.W.,Belshaw, S.,Pannifer, A.,Sime, M.,Bower, J.,Drysdale, M.,Olson, M.F. A novel small-molecule MRCK inhibitor blocks cancer cell invasion. Cell Commun. Signal, 12:54-54, 2014 Cited by PubMed: 25288205DOI: 10.1186/PREACCEPT-1467335606136283 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.73 Å) |
Structure validation
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