4U90
GephE in complex with PEG crosslinked GABA receptor alpha3 subunit derived dimeric peptide
Summary for 4U90
Entry DOI | 10.2210/pdb4u90/pdb |
Related | 4PD0 4PD1 4TK1 4TK2 4TK3 4TK4 4U91 |
Descriptor | Gephyrin, Gamma-aminobutyric acid receptor subunit alpha-3, 1,4-BUTANEDIOL, ... (5 entities in total) |
Functional Keywords | inhibitory synapse, scaffolding protein, gaba type a receptor, transferase, transfer protein - structural protein complex, transfer protein / structural protein |
Biological source | Rattus norvegicus (Rat) More |
Cellular location | Cell junction, synapse : Q03555 Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein: P20236 |
Total number of polymer chains | 3 |
Total formula weight | 48279.34 |
Authors | Kasaragod, V.B.,Maric, H.M.,Schindelin, H. (deposition date: 2014-08-05, release date: 2014-12-10, Last modification date: 2023-12-20) |
Primary citation | Maric, H.M.,Kasaragod, V.B.,Haugaard-Kedstrom, L.,Hausrat, T.J.,Kneussel, M.,Schindelin, H.,Strmgaard, K. Design and Synthesis of High-Affinity Dimeric Inhibitors Targeting the Interactions between Gephyrin and Inhibitory Neurotransmitter Receptors. Angew.Chem.Int.Ed.Engl., 54:490-494, 2015 Cited by PubMed: 25413248DOI: 10.1002/anie.201409043 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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