4U8C
Crystal structure of D(CGCGAATTCGCG)2 complexed with BPH-1409
Summary for 4U8C
Entry DOI | 10.2210/pdb4u8c/pdb |
Related | 4U8A 4U8B |
Descriptor | DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3'), MAGNESIUM ION, 2,2'-benzene-1,4-diylbis[6-(1,4,5,6-tetrahydropyrimidin-2-yl)-1H-indole], ... (4 entities in total) |
Functional Keywords | antibacterial agents, bisamidines, minor groove binders, models, molecular, nucleic acid conformation, oligodeoxyribonucleotides, dna-antibiotic complex, dna/antibiotic |
Biological source | synthetic construct |
Total number of polymer chains | 2 |
Total formula weight | 7823.67 |
Authors | Zhu, W.,Oldfield, E. (deposition date: 2014-08-01, release date: 2015-02-04, Last modification date: 2023-09-27) |
Primary citation | Zhu, W.,Wang, Y.,Li, K.,Gao, J.,Huang, C.H.,Chen, C.C.,Ko, T.P.,Zhang, Y.,Guo, R.T.,Oldfield, E. Antibacterial drug leads: DNA and enzyme multitargeting. J.Med.Chem., 58:1215-1227, 2015 Cited by PubMed: 25574764DOI: 10.1021/jm501449u PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.24 Å) |
Structure validation
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