4U6V
Mechanisms of Neutralization of a Human Anti-Alpha Toxin Antibody
Summary for 4U6V
Entry DOI | 10.2210/pdb4u6v/pdb |
Descriptor | Fab, antigen binding fragment, heavy chain, Fab, antigen binding fragment, light chain, Alpha-hemolysin, ... (5 entities in total) |
Functional Keywords | alpha toxin, fab, staphylococcus aureus, mutagenesis, immune system |
Biological source | Homo sapiens (Human) More |
Cellular location | Secreted : Q2G1X0 |
Total number of polymer chains | 6 |
Total formula weight | 161577.53 |
Authors | Oganesyan, V.Y.,Peng, L.,Damschroder, M.M.,Cheng, L.,Sadowska, A.,Tkaczyk, C.,Sellman, B.,Wu, H.,Dall'Acqua, W.F. (deposition date: 2014-07-29, release date: 2014-09-17, Last modification date: 2023-09-27) |
Primary citation | Oganesyan, V.,Peng, L.,Damschroder, M.M.,Cheng, L.,Sadowska, A.,Tkaczyk, C.,Sellman, B.R.,Wu, H.,Dall'Acqua, W.F. Mechanisms of Neutralization of a Human Anti-alpha-toxin Antibody. J.Biol.Chem., 289:29874-29880, 2014 Cited by PubMed: 25210036DOI: 10.1074/jbc.M114.601328 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.56 Å) |
Structure validation
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