4U6G

Crystal structure of 10E8 Fab in complex with a hydrocarbon-stapled HIV-1 gp41 MPER peptide

Summary for 4U6G

• Entry DOI: 10.2210/pdb4u6g/pdb
• Descriptor: 10E8 Fab Heavy Chain, 10E8 Fab Light Chain, SAH-MPER(662-683KKK)(B,q) (3 entities in total)
• Functional Keywords: 10e8 antibody, hiv-1, hydrocarbon-staple, gp41 mper, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 101257.10

Authors

Ofek, G.,Bird, G.H.,Walensky, L.D.,Kwong, P.D. (deposition date: 2014-07-28, release date: 2014-12-03, Last modification date: 2023-12-27)

• Primary citation: Bird, G.H.,Irimia, A.,Ofek, G.,Kwong, P.D.,Wilson, I.A.,Walensky, L.D.; Structural Fidelity and Neutralizing Antibody Binding Capacity of Hydrocarbon-Stapled HIV-1 Antigens; To be published,

Experimental method

X-RAY DIFFRACTION (4.2012 Å)