4U0P

The Crystal Structure of Lipoyl Synthase in Complex with S-Adenosyl Homocysteine

Summary for 4U0P

Entry DOI	10.2210/pdb4u0p/pdb
Descriptor	Lipoyl synthase 2, IRON/SULFUR CLUSTER, S-ADENOSYL-L-HOMOCYSTEINE, ... (5 entities in total)
Functional Keywords	thiotransferase, tim barrel, fes cluster, radical sam, transferase
Biological source	Thermosynechococcus elongatus
Cellular location	Cytoplasm : Q8DLC2
Total number of polymer chains	1
Total formula weight	33716.04
Authors	Harmer, J.E.,Hiscox, M.J.,Sandy, J.,Dinis, P.C.,Roach, P.L. (deposition date: 2014-07-13, release date: 2014-08-20, Last modification date: 2024-05-08)
Primary citation	Harmer, J.E.,Hiscox, M.J.,Dinis, P.C.,Fox, S.J.,Iliopoulos, A.,Hussey, J.E.,Sandy, J.,Van Beek, F.T.,Essex, J.W.,Roach, P.L. Structures of lipoyl synthase reveal a compact active site for controlling sequential sulfur insertion reactions. Biochem.J., 464:123-133, 2014 Cited by PubMed: 25100160 DOI: 10.1042/BJ20140895 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.623 Å)

Structure validation