4TXS

An Ligand-observed Mass Spectrometry-based Approach Integrated into the Fragment Based Lead Discovery Pipeline

4TXS の概要

• エントリーDOI: 10.2210/pdb4txs/pdb
• 関連するPDBエントリー: 4TXF 4TY8 4TY9 4TYA 4TYB
• 分子名称: Polyprotein, (4-hydroxyphenyl)acetonitrile (2 entities in total)
• 機能のキーワード: inhibitor, tetramer, ns5b, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Hepatitis C virus
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 251700.52

構造登録者

Shui, W.,Yang, C.,Lin, J.,Chen, X.,Qin, S.,Chen, S. (登録日: 2014-07-07, 公開日: 2015-05-06, 最終更新日: 2024-03-20)

• 主引用文献: Chen, X.,Qin, S.,Chen, S.,Li, J.,Li, L.,Wang, Z.,Wang, Q.,Lin, J.,Yang, C.,Shui, W.; A ligand-observed mass spectrometry approach integrated into the fragment based lead discovery pipeline; Sci Rep, 5:8361-8361, 2015; PubMed: 25666181; DOI: 10.1038/srep08361

実験手法

X-RAY DIFFRACTION (2.78 Å)