4TRT

Deinococcus radiodurans DNA polymerase III subunit beta

Summary for 4TRT

• Entry DOI: 10.2210/pdb4trt/pdb
• Descriptor: DNA polymerase III subunit beta (2 entities in total)
• Functional Keywords: dna clamp, transferase
• Biological source: Deinococcus radiodurans
• Cellular location: Cytoplasm : Q9RYE8
• Total number of polymer chains: 2
• Total formula weight: 79087.23

Authors

Niiranen, L.,Lian, K.,Johnson, K.A.,Moe, E. (deposition date: 2014-06-17, release date: 2015-04-29, Last modification date: 2023-12-20)

Primary citation

Niiranen, L.,Lian, K.,Johnson, K.A.,Moe, E.
Crystal structure of the DNA polymerase III beta subunit ( beta-clamp) from the extremophile Deinococcus radiodurans.
Bmc Struct.Biol., 15:5-5, 2015

PubMed Abstract: Deinococcus radiodurans is an extremely radiation and desiccation resistant bacterium which can tolerate radiation doses up to 5,000 Grays without losing viability. We are studying the role of DNA repair and replication proteins for this unusual phenotype by a structural biology approach. The DNA polymerase III β subunit (β-clamp) acts as a sliding clamp on DNA, promoting the binding and processivity of many DNA-acting proteins, and here we report the crystal structure of D. radiodurans β-clamp (Drβ-clamp) at 2.0 Å resolution.

PubMed: 25886944
DOI: 10.1186/s12900-015-0032-6

Experimental method

X-RAY DIFFRACTION (2 Å)