4TRT

Deinococcus radiodurans DNA polymerase III subunit beta

4TRT の概要

• エントリーDOI: 10.2210/pdb4trt/pdb
• 分子名称: DNA polymerase III subunit beta (2 entities in total)
• 機能のキーワード: dna clamp, transferase
• 由来する生物種: Deinococcus radiodurans
• 細胞内の位置: Cytoplasm : Q9RYE8
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 79087.23

構造登録者

Niiranen, L.,Lian, K.,Johnson, K.A.,Moe, E. (登録日: 2014-06-17, 公開日: 2015-04-29, 最終更新日: 2023-12-20)

主引用文献

Niiranen, L.,Lian, K.,Johnson, K.A.,Moe, E.
Crystal structure of the DNA polymerase III beta subunit ( beta-clamp) from the extremophile Deinococcus radiodurans.
Bmc Struct.Biol., 15:5-5, 2015

PubMed Abstract: Deinococcus radiodurans is an extremely radiation and desiccation resistant bacterium which can tolerate radiation doses up to 5,000 Grays without losing viability. We are studying the role of DNA repair and replication proteins for this unusual phenotype by a structural biology approach. The DNA polymerase III β subunit (β-clamp) acts as a sliding clamp on DNA, promoting the binding and processivity of many DNA-acting proteins, and here we report the crystal structure of D. radiodurans β-clamp (Drβ-clamp) at 2.0 Å resolution.

PubMed: 25886944
DOI: 10.1186/s12900-015-0032-6

実験手法

X-RAY DIFFRACTION (2 Å)