4TKY

The complex structure of E. coli DsbA bound to a peptide at the DsbA/DsbB interface

4TKY の概要

• エントリーDOI: 10.2210/pdb4tky/pdb
• 分子名称: Thiol:disulfide interchange protein DsbA, PRO-PHE-ALA-THR-CYS-ASP-SER, ACETYL GROUP, ... (5 entities in total)
• 機能のキーワード: dsba, dsbb, dithiol oxidase, complex, dsba/dsbb, peptide inhibitor, thioredoxin-related protein, oxidoreductase-peptide inhibitor complex, oxidoreductase/peptide inhibitor
• 由来する生物種: Escherichia coli; 詳細
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 88496.04

構造登録者

Premkumar, L.,Martin, J.L. (登録日: 2014-05-28, 公開日: 2015-01-14, 最終更新日: 2023-09-27)

• 主引用文献: Duprez, W.,Premkumar, L.,Halili, M.A.,Lindahl, F.,Reid, R.C.,Fairlie, D.P.,Martin, J.L.; Peptide Inhibitors of the Escherichia coli DsbA Oxidative Machinery Essential for Bacterial Virulence.; J.Med.Chem., 58:577-587, 2015; PubMed: 25470204; DOI: 10.1021/jm500955s

実験手法

X-RAY DIFFRACTION (2.5 Å)