4S2K

OXA-48 in complex with Avibactam at pH 7.5

Summary for 4S2K

Entry DOI	10.2210/pdb4s2k/pdb
Descriptor	Beta-lactamase, (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide (3 entities in total)
Functional Keywords	inhibitor, beta-lactamase, hydrolase-antibiotic complex, hydrolase/antibiotic
Biological source	Klebsiella pneumoniae
Total number of polymer chains	4
Total formula weight	122655.92
Authors	King, D.T.,Strynadka, N.C.J. (deposition date: 2015-01-20, release date: 2015-02-25, Last modification date: 2023-09-20)
Primary citation	King, D.T.,King, A.M.,Lal, S.M.,Wright, G.D.,Strynadka, N.C. Molecular Mechanism of Avibactam-Mediated beta-Lactamase Inhibition. ACS Infect Dis, 1:175-184, 2015 Cited by PubMed: 27622530 DOI: 10.1021/acsinfecdis.5b00007 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation