4S2K
OXA-48 in complex with Avibactam at pH 7.5
Summary for 4S2K
Entry DOI | 10.2210/pdb4s2k/pdb |
Descriptor | Beta-lactamase, (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide (3 entities in total) |
Functional Keywords | inhibitor, beta-lactamase, hydrolase-antibiotic complex, hydrolase/antibiotic |
Biological source | Klebsiella pneumoniae |
Total number of polymer chains | 4 |
Total formula weight | 122655.92 |
Authors | King, D.T.,Strynadka, N.C.J. (deposition date: 2015-01-20, release date: 2015-02-25, Last modification date: 2023-09-20) |
Primary citation | King, D.T.,King, A.M.,Lal, S.M.,Wright, G.D.,Strynadka, N.C. Molecular Mechanism of Avibactam-Mediated beta-Lactamase Inhibition. ACS Infect Dis, 1:175-184, 2015 Cited by PubMed: 27622530DOI: 10.1021/acsinfecdis.5b00007 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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