4S0L

Biphenylalanine modified threonyl-tRNA synthetase from Pyrococcus abyssi: I11BIF, Y79V, and F123V mutant

Summary for 4S0L

• Entry DOI: 10.2210/pdb4s0l/pdb
• Related: 1y2q
• Descriptor: Threonine--tRNA ligase (2 entities in total)
• Functional Keywords: beta-alpha-beta fold, editing domain, trna-synthetase, ligase, biphenylalanine, unnatural amino acid, threonine-trna ligase
• Biological source: Pyrococcus abyssi GE5
• Cellular location: Cytoplasm : Q9UZ14
• Total number of polymer chains: 1
• Total formula weight: 17357.99

Authors

Pearson, A.D.,Mills, J.H.,Song, Y.,Nasertorabi, F.,Han, G.W.,Baker, D.,Stevens, R.C.,Schultz, P.G. (deposition date: 2014-12-31, release date: 2015-03-18, Last modification date: 2023-09-20)

• Primary citation: Pearson, A.D.,Mills, J.H.,Song, Y.,Nasertorabi, F.,Han, G.W.,Baker, D.,Stevens, R.C.,Schultz, P.G.; Transition states. Trapping a transition state in a computationally designed protein bottle.; Science, 347:863-867, 2015; PubMed: 25700516; DOI: 10.1126/science.aaa2424

Experimental method

X-RAY DIFFRACTION (2.5 Å)