4RVC

Structure of ATP binding subunit of ABC transporter

4RVC の概要

• エントリーDOI: 10.2210/pdb4rvc/pdb
• 分子名称: ABC transporter ATP-binding protein (2 entities in total)
• 機能のキーワード: motif c, atp bindig, transport protein
• 由来する生物種: Geobacillus kaustophilus
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 27554.91

構造登録者

Manjula, M.,Pampa, K.J.,Lokanath, N.K. (登録日: 2014-11-26, 公開日: 2015-03-18, 最終更新日: 2024-02-28)

主引用文献

Manjula, M.,Pampa, K.J.,Kumar, S.M.,Mukherjee, S.,Kunishima, N.,Rangappa, K.S.,Lokanath, N.K.
Crystal structure of ATP-binding subunit of an ABC transporter from Geobacillus kaustophilus.
Biochem.Biophys.Res.Commun., 459:113-117, 2015

PubMed Abstract: The ATP binding cassette (ABC) transporters, represent one of the largest superfamilies of primary transporters, which are very essential for various biological functions. The crystal structure of ATP-binding subunit of an ABC transporter from Geobacillus kaustophilus has been determined at 1.77 Å resolution. The crystal structure revealed that the protomer has two thick arms, (arm I and II), which resemble 'L' shape. The ATP-binding pocket is located close to the end of arm I. ATP molecule is docked into the active site of the protein. The dimeric crystal structure of ATP-binding subunit of ABC transporter from G. kaustophilus has been compared with the previously reported crystal structure of ATP-binding subunit of ABC transporter from Salmonella typhimurium.

PubMed: 25724946
DOI: 10.1016/j.bbrc.2015.02.079

実験手法

X-RAY DIFFRACTION (1.77 Å)