4RUX
Crystal structure of human Carbonic Anhydrase II in complex with 4-(allyloxy)benzenesulfonamide
Summary for 4RUX
| Entry DOI | 10.2210/pdb4rux/pdb |
| Related | 4RUY 4RUZ |
| Descriptor | Carbonic anhydrase 2, ZINC ION, 4-(allyloxy)benzenesulfonamide, ... (5 entities in total) |
| Functional Keywords | metalloenzyme, analgesic, lyase |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm : P00918 |
| Total number of polymer chains | 1 |
| Total formula weight | 29873.07 |
| Authors | Pinard, M.A.,Mckenna, R. (deposition date: 2014-11-23, release date: 2015-04-22, Last modification date: 2024-02-28) |
| Primary citation | Carta, F.,Di Cesare Mannelli, L.,Pinard, M.,Ghelardini, C.,Scozzafava, A.,McKenna, R.,Supuran, C.T. A class of sulfonamide carbonic anhydrase inhibitors with neuropathic pain modulating effects. Bioorg.Med.Chem., 23:1828-1840, 2015 Cited by PubMed: 25766630DOI: 10.1016/j.bmc.2015.02.027 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.14 Å) |
Structure validation
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