4RUT

crystal structure of murine cyclooxygenase-2 with 13-methyl-arachidonic Acid

4RUT の概要

• エントリーDOI: 10.2210/pdb4rut/pdb
• 分子名称: Prostaglandin G/H synthase 2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• 機能のキーワード: protein-ligand complex, prostaglandin-endoperoxide synthase, fatty acid analog, oxidoreductase, glycosylation, membrane
• 由来する生物種: Mus musculus (mouse)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 277135.12

構造登録者

Xu, S.,Kudalkar, S.N.,Banerjee, S.,Makriyannis, A.,Nikas, S.P.,Marnett, L.J. (登録日: 2014-11-21, 公開日: 2015-02-11, 最終更新日: 2023-09-20)

• 主引用文献: Kudalkar, S.N.,Nikas, S.P.,Kingsley, P.J.,Xu, S.,Galligan, J.J.,Rouzer, C.A.,Banerjee, S.,Ji, L.,Eno, M.R.,Makriyannis, A.,Marnett, L.J.; 13-methylarachidonic Acid is a positive allosteric modulator of endocannabinoid oxygenation by cyclooxygenase.; J.Biol.Chem., 290:7897-7909, 2015; PubMed: 25648895; DOI: 10.1074/jbc.M114.634014

実験手法

X-RAY DIFFRACTION (2.16 Å)