4RNQ
Crystal structure of tobacco 5-epi-aristolochene synthase (TEAS) with anilinogeranyl diphosphate (AGPP) and geraniline
Summary for 4RNQ
Entry DOI | 10.2210/pdb4rnq/pdb |
Descriptor | 5-epi-aristolochene synthase, MAGNESIUM ION, (2E,6E)-3,7-dimethyl-8-(phenylamino)octa-2,6-dien-1-yl trihydrogen diphosphate, ... (7 entities in total) |
Functional Keywords | teas, 5-epi-aristolochene synthase, anilinogeranyl diphosphate (agpp), geraniline, terpene synthase, lyase |
Biological source | Nicotiana tabacum (American tobacco,tobacco) |
Cellular location | Cytoplasm: Q40577 |
Total number of polymer chains | 1 |
Total formula weight | 64140.27 |
Authors | Koo, H.J.,Crenshaw, C.M.,Starks, C.,Spielmann, H.P.,Chappell, J.,Noel, J.P. (deposition date: 2014-10-24, release date: 2015-05-06, Last modification date: 2024-02-28) |
Primary citation | Rising, K.A.,Crenshaw, C.M.,Koo, H.J.,Subramanian, T.,Chehade, K.A.,Starks, C.,Allen, K.D.,Andres, D.A.,Spielmann, H.P.,Noel, J.P.,Chappell, J. Formation of a Novel Macrocyclic Alkaloid from the Unnatural Farnesyl Diphosphate Analogue Anilinogeranyl Diphosphate by 5-Epi-Aristolochene Synthase. Acs Chem.Biol., 10:1729-1736, 2015 Cited by PubMed: 25897591DOI: 10.1021/acschembio.5b00145 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.47 Å) |
Structure validation
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