4RNQ

Crystal structure of tobacco 5-epi-aristolochene synthase (TEAS) with anilinogeranyl diphosphate (AGPP) and geraniline

4RNQ の概要

• エントリーDOI: 10.2210/pdb4rnq/pdb
• 分子名称: 5-epi-aristolochene synthase, MAGNESIUM ION, (2E,6E)-3,7-dimethyl-8-(phenylamino)octa-2,6-dien-1-yl trihydrogen diphosphate, ... (7 entities in total)
• 機能のキーワード: teas, 5-epi-aristolochene synthase, anilinogeranyl diphosphate (agpp), geraniline, terpene synthase, lyase
• 由来する生物種: Nicotiana tabacum (American tobacco,tobacco)
• 細胞内の位置: Cytoplasm: Q40577
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 64140.27

構造登録者

Koo, H.J.,Crenshaw, C.M.,Starks, C.,Spielmann, H.P.,Chappell, J.,Noel, J.P. (登録日: 2014-10-24, 公開日: 2015-05-06, 最終更新日: 2024-02-28)

• 主引用文献: Rising, K.A.,Crenshaw, C.M.,Koo, H.J.,Subramanian, T.,Chehade, K.A.,Starks, C.,Allen, K.D.,Andres, D.A.,Spielmann, H.P.,Noel, J.P.,Chappell, J.; Formation of a Novel Macrocyclic Alkaloid from the Unnatural Farnesyl Diphosphate Analogue Anilinogeranyl Diphosphate by 5-Epi-Aristolochene Synthase.; Acs Chem.Biol., 10:1729-1736, 2015; PubMed: 25897591; DOI: 10.1021/acschembio.5b00145

実験手法

X-RAY DIFFRACTION (2.47 Å)