4R8W

Crystal structure of H7 hemagglutinin from A/Anhui/1/2013 in complex with a neutralizing antibody CT149

Summary for 4R8W

• Entry DOI: 10.2210/pdb4r8w/pdb
• Descriptor: Hemagglutinin, Heavy chain of neutralizing antibody CT149, Light chain of neutralizing antibody CT149, ... (6 entities in total)
• Functional Keywords: influenza a virus, hemagglutinin, neutralizing antibody, immune system
• Biological source: Influenza A virus (A/Anhui/1-BALF_RG45/2013(H7N9)); More
• Total number of polymer chains: 4
• Total formula weight: 104290.33

Authors

Wu, Y.,Shi, Y.,Qi, J.,Gao, G.F. (deposition date: 2014-09-03, release date: 2015-08-26, Last modification date: 2023-11-08)

• Primary citation: Wu, Y.,Cho, M.,Shore, D.,Song, M.,Choi, J.,Jiang, T.,Deng, Y.Q.,Bourgeois, M.,Almli, L.,Yang, H.,Chen, L.M.,Shi, Y.,Qi, J.,Li, A.,Yi, K.S.,Chang, M.,Bae, J.S.,Lee, H.,Shin, J.,Stevens, J.,Hong, S.,Qin, C.F.,Gao, G.F.,Chang, S.J.,Donis, R.O.; A potent broad-spectrum protective human monoclonal antibody crosslinking two haemagglutinin monomers of influenza A virus; Nat Commun, 6:7708-7708, 2015; PubMed: 26196962; DOI: 10.1038/ncomms8708

Experimental method

X-RAY DIFFRACTION (2.795 Å)