4R8H
The role of protein-ligand contacts in allosteric regulation of the Escherichia coli Catabolite Activator Protein
Summary for 4R8H
Entry DOI | 10.2210/pdb4r8h/pdb |
Descriptor | cAMP-activated global transcriptional regulator CRP, 6-(6-AMINO-PURIN-9-YL)-2-THIOXO-TETRAHYDRO-2-FURO[3,2-D][1,3,2]DIOXAPHOSPHININE-2,7-DIOL, GLYCEROL, ... (4 entities in total) |
Functional Keywords | transcription factor, transcription |
Biological source | Escherichia coli |
Total number of polymer chains | 2 |
Total formula weight | 52181.70 |
Authors | Townsend, P.D.,Pohl, E.,McLeish, T.C.B.,Rodgers, T.L.,Glover, L.C.,Korhonen, H.J.,Wilson, M.R.,Hodgson, D.R.W.,Cann, M.J. (deposition date: 2014-09-02, release date: 2015-07-22, Last modification date: 2024-02-28) |
Primary citation | Townsend, P.D.,Rodgers, T.L.,Glover, L.C.,Korhonen, H.J.,Richards, S.A.,Colwell, L.J.,Pohl, E.,Wilson, M.R.,Hodgson, D.R.,McLeish, T.C.,Cann, M.J. The Role of Protein-Ligand Contacts in Allosteric Regulation of the Escherichia coli Catabolite Activator Protein. J.Biol.Chem., 290:22225-22235, 2015 Cited by PubMed: 26187469DOI: 10.1074/jbc.M115.669267 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.46 Å) |
Structure validation
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