4R8H

The role of protein-ligand contacts in allosteric regulation of the Escherichia coli Catabolite Activator Protein

4R8H の概要

• エントリーDOI: 10.2210/pdb4r8h/pdb
• 分子名称: cAMP-activated global transcriptional regulator CRP, 6-(6-AMINO-PURIN-9-YL)-2-THIOXO-TETRAHYDRO-2-FURO[3,2-D][1,3,2]DIOXAPHOSPHININE-2,7-DIOL, GLYCEROL, ... (4 entities in total)
• 機能のキーワード: transcription factor, transcription
• 由来する生物種: Escherichia coli
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 52181.70

構造登録者

Townsend, P.D.,Pohl, E.,McLeish, T.C.B.,Rodgers, T.L.,Glover, L.C.,Korhonen, H.J.,Wilson, M.R.,Hodgson, D.R.W.,Cann, M.J. (登録日: 2014-09-02, 公開日: 2015-07-22, 最終更新日: 2024-02-28)

• 主引用文献: Townsend, P.D.,Rodgers, T.L.,Glover, L.C.,Korhonen, H.J.,Richards, S.A.,Colwell, L.J.,Pohl, E.,Wilson, M.R.,Hodgson, D.R.,McLeish, T.C.,Cann, M.J.; The Role of Protein-Ligand Contacts in Allosteric Regulation of the Escherichia coli Catabolite Activator Protein.; J.Biol.Chem., 290:22225-22235, 2015; PubMed: 26187469; DOI: 10.1074/jbc.M115.669267

実験手法

X-RAY DIFFRACTION (1.46 Å)