Crystal Structure of a De Novo Designed Beta Sheet Protein, Cystatin Fold, Northeast Structural Genomics Consortium (NESG) Target OR486

Summary for 4R80

DescriptorOR486 (2 entities in total)
Functional Keywordsstructural genomics, psi-biology, protein structure initiative, northeast structural genomics consortium (nesg), target or486, protein engineering, denovo beta sheet design, cystatin fold, de novo protein
Biological sourcesynthetic construct (artificial gene)
Total number of polymer chains2
Total molecular weight19794.34
Primary citation
Guan, R.,Marcos, E.,O'Connell, P.,Seetharaman, J.,Janjua, H.,Xiao, R.,Maglaqui, M.,Acton, T.B.,Everett, J.K.,Baker, D.,Montelione, G.T.,Northeast Structural Genomics Consortium (NESG)
Crystal Structure of an engineered protein with denovo beta sheet design, Northeast Structural Genomics Consortium (NESG) Target OR486
To be Published,
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.2567004.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report