4QY8

Crystal Structure of anti-MSP2 Fv fragment (mAb6D8) in complex with 3D7-MSP2 14-30

Summary for 4QY8

Entry DOI	10.2210/pdb4qy8/pdb
Related	4QXT 4QYO
Descriptor	Fv fragment(mAb6D8) heavy chain, Fv fragment(mAb6D8) light chain, Merozoite surface antigen 2, ... (4 entities in total)
Functional Keywords	immunoglobulin fold, immune system, n-terminal msp2, unstructured antigen
Biological source	Mus musculus More
Cellular location	Cell membrane; Lipid-anchor, GPI-anchor: P50498
Total number of polymer chains	3
Total formula weight	26418.22
Authors	Morales, R.A.V.,MacRaild, C.A.,Seow, J.,Bankala, K.,Drinkwater, N.,McGowan, S.,Rouet, R.,Christ, D.,Anders, R.F.,Norton, R.S. (deposition date: 2014-07-24, release date: 2015-06-03, Last modification date: 2023-11-08)
Primary citation	Morales, R.A.,MacRaild, C.A.,Seow, J.,Krishnarjuna, B.,Drinkwater, N.,Rouet, R.,Anders, R.F.,Christ, D.,McGowan, S.,Norton, R.S. Structural basis for epitope masking and strain specificity of a conserved epitope in an intrinsically disordered malaria vaccine candidate. Sci Rep, 5:10103-10103, 2015 Cited by PubMed: 25965408 DOI: 10.1038/srep10103 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.353 Å)

Structure validation