4QO0
Crystal structure of rhomboid intramembrane protease GlpG in complex with peptide derived inhibitor Ac-FATA-cmk
Summary for 4QO0
Entry DOI | 10.2210/pdb4qo0/pdb |
Related | 4QNZ |
Related PRD ID | PRD_001251 |
Descriptor | Rhomboid protease GlpG, ACE-PHE-ALA-THR-ALA-0QE, CHLORIDE ION, ... (5 entities in total) |
Functional Keywords | alpha-helical, rhomboid intramembrane protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Escherichia coli |
Cellular location | Cell inner membrane; Multi-pass membrane protein (By similarity). Cell membrane; Multi-pass membrane protein (By similarity): U6NA71 |
Total number of polymer chains | 2 |
Total formula weight | 23853.12 |
Authors | Zoll, S.,Strisovsky, K. (deposition date: 2014-06-19, release date: 2014-09-24, Last modification date: 2023-09-20) |
Primary citation | Zoll, S.,Stanchev, S.,Began, J.,Skerle, J.,Lepsik, M.,Peclinovska, L.,Majer, P.,Strisovsky, K. Substrate binding and specificity of rhomboid intramembrane protease revealed by substrate-peptide complex structures. Embo J., 33:2408-2421, 2014 Cited by PubMed: 25216680DOI: 10.15252/embj.201489367 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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