4QNP

Crystal structure of the 2009 pandemic H1N1 influenza virus neuraminidase with a neutralizing antibody

Summary for 4QNP

• Entry DOI: 10.2210/pdb4qnp/pdb
• Descriptor: Neuraminidase, neutralizing antibody, light chain, neutralizing antibody, heavy chain, ... (7 entities in total)
• Functional Keywords: influenza, neuraminidase, antibody, neutralizing antibody, hydrolase-immune system complex, hydrolase/immune system
• Biological source: Influenza A virus; More
• Cellular location: Virion membrane : S5N0T0
• Total number of polymer chains: 6
• Total formula weight: 181924.46

Authors

Wan, H.Q.,Yang, H.,Shore, D.A.,Garten, R.J.,Couzens, L.,Gao, J.,Jiang, L.L.,Carney, P.J.,Villanueva, J.,Stevens, J.,Eichelberger, M.C. (deposition date: 2014-06-18, release date: 2015-02-11, Last modification date: 2023-09-20)

• Primary citation: Wan, H.,Yang, H.,Shore, D.A.,Garten, R.J.,Couzens, L.,Gao, J.,Jiang, L.,Carney, P.J.,Villanueva, J.,Stevens, J.,Eichelberger, M.C.; Structural characterization of a protective epitope spanning A(H1N1)pdm09 influenza virus neuraminidase monomers.; Nat Commun, 6:6114-6114, 2015; PubMed: 25668439; DOI: 10.1038/ncomms7114

Experimental method

X-RAY DIFFRACTION (2.8 Å)