4Q7Z
Neutrophil serine protease 4 (PRSS57) with phe-phe-arg-chloromethylketone (FFR-cmk)
Summary for 4Q7Z
| Entry DOI | 10.2210/pdb4q7z/pdb |
| Related | 4Q7X 4Q7Y 4Q80 |
| Related PRD ID | PRD_001231 |
| Descriptor | Serine protease 57, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total) |
| Functional Keywords | trypsin homology, peptidase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasmic granule lumen : Q6UWY2 |
| Total number of polymer chains | 1 |
| Total formula weight | 28222.04 |
| Authors | Eigenbrot, C.,Lin, S.J.,Dong, K.C. (deposition date: 2014-04-25, release date: 2014-09-03, Last modification date: 2023-09-20) |
| Primary citation | Lin, S.J.,Dong, K.C.,Eigenbrot, C.,van Lookeren Campagne, M.,Kirchhofer, D. Structures of neutrophil serine protease 4 reveal an unusual mechanism of substrate recognition by a trypsin-fold protease. Structure, 22:1333-1340, 2014 Cited by PubMed: 25156428DOI: 10.1016/j.str.2014.07.008 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
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