4Q1U

Serum paraoxonase-1 by directed evolution with the K192Q mutation

Summary for 4Q1U

Entry DOI	10.2210/pdb4q1u/pdb
Related	1V04 3SRE 3SRG 4HHO
Descriptor	Serum paraoxonase/arylesterase 1, CALCIUM ION, DODECYL-BETA-D-MALTOSIDE, ... (7 entities in total)
Functional Keywords	6-blades-propeller fold, lactonase, hydrolase
Biological source	hybrid
Total number of polymer chains	1
Total formula weight	40375.98
Authors	Ben-David, M.,Sussman, J.L.,Tawfik, D.S. (deposition date: 2014-04-04, release date: 2015-02-18, Last modification date: 2023-09-20)
Primary citation	Ben-David, M.,Sussman, J.L.,Maxwell, C.I.,Szeler, K.,Kamerlin, S.C.,Tawfik, D.S. Catalytic stimulation by restrained active-site floppiness-the case of high density lipoprotein-bound serum paraoxonase-1. J.Mol.Biol., 427:1359-1374, 2015 Cited by PubMed: 25644661 DOI: 10.1016/j.jmb.2015.01.013 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.302 Å)

Structure validation