4PXI

Elucidation of the Structural and Functional Mechanism of Action of the TetR Family Protein, CprB from S. coelicolor A3(2)

Summary for 4PXI

• Entry DOI: 10.2210/pdb4pxi/pdb
• Related: 1UI5
• Descriptor: CprB, DNA (5'-D(*AP*CP*AP*TP*AP*CP*GP*GP*GP*AP*CP*GP*CP*CP*CP*CP*GP*TP*TP*TP*AP*T)-3'), DNA (5'-D(*AP*TP*AP*AP*AP*CP*GP*GP*GP*GP*CP*GP*TP*CP*CP*CP*GP*TP*AP*TP*GP*T)-3') (3 entities in total)
• Functional Keywords: cprb-dna complex, tetr superfamily of transcription regulators, a-factor receptor homolog protein, cprb, autoregulator, s. coelicolor a3(2), gamma-butryolactones receptor protein, transcription-dna complex, transcription/dna
• Biological source: Streptomyces coelicolor; More
• Total number of polymer chains: 6
• Total formula weight: 108382.04

Authors

Hussain, B.,Ruchika, B.,Aruna, B.,Ruchi, A. (deposition date: 2014-03-24, release date: 2014-07-02, Last modification date: 2023-11-08)

• Primary citation: Bhukya, H.,Bhujbalrao, R.,Bitra, A.,Anand, R.; Structural and functional basis of transcriptional regulation by TetR family protein CprB from S. coelicolor A3(2); Nucleic Acids Res., 42:10122-10133, 2014; PubMed: 25092919; DOI: 10.1093/nar/gku587

Experimental method

X-RAY DIFFRACTION (3.2 Å)