4PQG

Crystal structure of the pneumococcal O-GlcNAc transferase GtfA in complex with UDP and GlcNAc

4PQG の概要

• エントリーDOI: 10.2210/pdb4pqg/pdb
• 分子名称: Glycosyltransferase Gtf1, URIDINE-5'-DIPHOSPHATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• 機能のキーワード: o-glcnac transferase, gt-b fold, rossmann fold, gtfb, transferase
• 由来する生物種: Streptococcus pneumoniae
• 細胞内の位置: Cytoplasm: Q97P84
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 118970.18

構造登録者

Shi, W.W.,Jiang, Y.L.,Zhu, F.,Yang, Y.H.,Wu, H.,Ren, Y.M.,Chen, Y.,Zhou, C.Z. (登録日: 2014-03-03, 公開日: 2014-06-18, 最終更新日: 2024-02-28)

• 主引用文献: Shi, W.W.,Jiang, Y.L.,Zhu, F.,Yang, Y.H.,Shao, Q.Y.,Yang, H.B.,Ren, Y.M.,Wu, H.,Chen, Y.,Zhou, C.Z.; Structure of a Novel O-Linked N-Acetyl-d-glucosamine (O-GlcNAc) Transferase, GtfA, Reveals Insights into the Glycosylation of Pneumococcal Serine-rich Repeat Adhesins.; J.Biol.Chem., 289:20898-20907, 2014; PubMed: 24936067; DOI: 10.1074/jbc.M114.581934

実験手法

X-RAY DIFFRACTION (2 Å)