4PQA

Crystal Structure of succinyl-diaminopimelate desuccinylase from Neisseria meningitidis MC58 in complex with the Inhibitor Captopril

Summary for 4PQA

Entry DOI	10.2210/pdb4pqa/pdb
Descriptor	Succinyl-diaminopimelate desuccinylase, L-CAPTOPRIL, SULFATE ION, ... (5 entities in total)
Functional Keywords	captopril, m20 aminopeptidase, dape, csgid, metaloenzyme, structural genomics, niaid, national institute of allergy and infectious diseases, center for structural genomics of infectious diseases, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Neisseria meningitidis
Total number of polymer chains	1
Total formula weight	41817.78
Authors	Nocek, B.,Starus, A.,Holz, R.,Anderson, W.F.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2014-03-01, release date: 2014-04-30, Last modification date: 2024-02-28)
Primary citation	Starus, A.,Nocek, B.,Bennett, B.,Larrabee, J.A.,Shaw, D.L.,Sae-Lee, W.,Russo, M.T.,Gillner, D.M.,Makowska-Grzyska, M.,Joachimiak, A.,Holz, R.C. Inhibition of the dapE-Encoded N-Succinyl-L,L-diaminopimelic Acid Desuccinylase from Neisseria meningitidis by L-Captopril. Biochemistry, 54:4834-4844, 2015 Cited by PubMed: 26186504 DOI: 10.1021/acs.biochem.5b00475 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.78 Å)

Structure validation