4PQA

Crystal Structure of succinyl-diaminopimelate desuccinylase from Neisseria meningitidis MC58 in complex with the Inhibitor Captopril

4PQA の概要

• エントリーDOI: 10.2210/pdb4pqa/pdb
• 分子名称: Succinyl-diaminopimelate desuccinylase, L-CAPTOPRIL, SULFATE ION, ... (5 entities in total)
• 機能のキーワード: captopril, m20 aminopeptidase, dape, csgid, metaloenzyme, structural genomics, niaid, national institute of allergy and infectious diseases, center for structural genomics of infectious diseases, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Neisseria meningitidis
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 41817.78

構造登録者

Nocek, B.,Starus, A.,Holz, R.,Anderson, W.F.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) (登録日: 2014-03-01, 公開日: 2014-04-30, 最終更新日: 2024-02-28)

• 主引用文献: Starus, A.,Nocek, B.,Bennett, B.,Larrabee, J.A.,Shaw, D.L.,Sae-Lee, W.,Russo, M.T.,Gillner, D.M.,Makowska-Grzyska, M.,Joachimiak, A.,Holz, R.C.; Inhibition of the dapE-Encoded N-Succinyl-L,L-diaminopimelic Acid Desuccinylase from Neisseria meningitidis by L-Captopril.; Biochemistry, 54:4834-4844, 2015; PubMed: 26186504; DOI: 10.1021/acs.biochem.5b00475

実験手法

X-RAY DIFFRACTION (1.78 Å)