4PJA

Structure of human MR1-5-OP-RU in complex with human MAIT B-B10 TCR

4PJA の概要

• エントリーDOI: 10.2210/pdb4pja/pdb
• 関連するPDBエントリー: 4L4T 4NQC 4PJ5 4PJ7 4PJ8 4PJ9 4PJB 4PJC 4PJD 4PJE 4PJF 4PJG 4PJH 4PJI 4PJX
• 分子名称: Major histocompatibility complex class I-related gene protein, Beta-2-microglobulin, TCR-alpha, ... (7 entities in total)
• 機能のキーワード: mr1, tcr, immune complex, 5-op-ru, immune system
• 由来する生物種: Homo sapiens (Human); 詳細
• 細胞内の位置: Cell membrane; Single-pass membrane protein; Extracellular side. Isoform 4: Secreted. Isoform 3: Cell membrane; Single-pass type I membrane protein: Q95460; Secreted: P61769
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 188950.90

構造登録者

Birkinshaw, R.W.,Rossjohn, J. (登録日: 2014-05-12, 公開日: 2014-07-02, 最終更新日: 2023-12-27)

• 主引用文献: Eckle, S.B.,Birkinshaw, R.W.,Kostenko, L.,Corbett, A.J.,McWilliam, H.E.,Reantragoon, R.,Chen, Z.,Gherardin, N.A.,Beddoe, T.,Liu, L.,Patel, O.,Meehan, B.,Fairlie, D.P.,Villadangos, J.A.,Godfrey, D.I.,Kjer-Nielsen, L.,McCluskey, J.,Rossjohn, J.; A molecular basis underpinning the T cell receptor heterogeneity of mucosal-associated invariant T cells.; J.Exp.Med., 211:1585-1600, 2014; PubMed: 25049336; DOI: 10.1084/jem.20140484

実験手法

X-RAY DIFFRACTION (2.68 Å)