4PIY
Homocysteine bound Cysteine Dioxygenase C93A variant at pH 6.2
Summary for 4PIY
Entry DOI | 10.2210/pdb4piy/pdb |
Related | 4IEO 4IEP 4IEQ 4IER 4IES 4IET 4IEU 4IEV 4IEW 4IEX 4IEY 4IEZ 4JTN 4JTO |
Descriptor | Cysteine dioxygenase type 1, FE (III) ION, 2-AMINO-4-MERCAPTO-BUTYRIC ACID, ... (4 entities in total) |
Functional Keywords | cupin fold, catalyzes oxidation, cysteine to cysteine sulfinate, c93-y157 crosslink, cytosol, oxidoreductase |
Biological source | Rattus norvegicus (Rat) |
Total number of polymer chains | 1 |
Total formula weight | 23217.85 |
Authors | Driggers, C.M.,Karplus, P.A. (deposition date: 2014-05-09, release date: 2016-02-17, Last modification date: 2024-04-03) |
Primary citation | Driggers, C.M.,Kean, K.M.,Hirschberger, L.L.,Cooley, R.B.,Stipanuk, M.H.,Karplus, P.A. Structure-Based Insights into the Role of the Cys-Tyr Crosslink and Inhibitor Recognition by Mammalian Cysteine Dioxygenase. J. Mol. Biol., 428:3999-4012, 2016 Cited by PubMed: 27477048DOI: 10.1016/j.jmb.2016.07.012 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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